![]() ![]() The control group consisted of 122 individuals who did not inhale the drug mixture, and were chosen randomly from the general population (NO-INH group). A questionnaire was completed in both groups, as well as IgE determination and lung function tests (spirometry and methacholine challenge). Ninety-one subjects who inhaled the drug mixture were included in the study: 62 subjects were from a drug rehabilitation center (INH-I group), and 29 subjects were among patients admitted to our hospital for a variety of reasons (INH-II group). To define the prevalence and the characteristics of bronchial disease (wheezing, bronchial hyperreactivity, and asthma) present in subjects inhaling heroin mixed with cocaine vaporized on aluminum foil. (1) There is a real increase in BHR in subjects who inhale heroin mixed with cocaine vaporized on aluminum foil and (2) this BHR is associated with wheezing that develops after a variable period of latency, once drug inhalation begins, and persists despite discontinuation of the drug.In our area, inhaling heroin mixed with cocaine vaporized on aluminum foil, known as rebujo, is becoming more and more common. Wheezing remitted in only 7.6% after discontinuation of the drug. Of the subjects who inhaled the drug mixture and denied having symptoms prior to the use of the drug mixture, 31.4% had wheezing develop after commencing use of the drug, following a mean latency of 4.09 months. In the INH-I group, there was a 41.9% prevalence of wheezing over the past 12 months, a 44.4% prevalence of BHR, and a 22.02% prevalence of asthma, defined as wheezing plus BHR. ![]() ![]() ![]() In our area, inhaling heroin mixed with cocaine vaporized on aluminum foil, known as rebujo, is becoming more and more common. ![]()
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